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Longevity pillar · Singapore

Gut Microbiome Testing in Singapore

The microbial ecosystem in your gut shapes digestion, immunity, mood, inflammation and metabolism. We sequence the microorganisms present in your sample and report both who is there and what they are functionally doing.

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  • SMC-registered doctors
  • MOH-licensed clinic (HCSA)
  • Mandarin Gallery, Orchard Road
  • Weekdays 10am-7pm · Sat-Sun 10am-5pm
  • パーソナルヘルスコンシェルジュ

測定内容

Species identification

Bacteria and other microorganisms present in your gut, identified from the DNA in your sample.

微生物の多様性

多様性スコアと、有益な微生物対日和見微生物の相対的なバランス。

機能遺伝子プロファイル

微生物が実際に何を行っているか（短鎖脂肪酸の産生、ビタミンの合成、代謝能力など） - 単に誰が存在するかだけでなく、その機能を解析します。

ディスバイオシス（腸内細菌叢の乱れ）および炎症マーカー

リーキーガットのリスク、慢性炎症、免疫シグナルの変化に関連するシグネチャー。

検査の仕組み

サンプル

在宅用便採取キット。数日間常温保存可能。冷蔵不要です。

所要時間

Your personal health concierge confirms the reporting timeline for your laboratory when your sample is collected.

手法

DNA sequencing of the microorganisms in your stool sample, mapped against reference databases.

この手法の理由

The report is read alongside your bloods and body composition by our medical team, then translated into a practical plan in an action-plan session. A test result on its own is not a plan.

わかること

  • 微生物の多様性が健康な範囲内にあるかどうか。
  • 不足している有益な菌種と、過剰に存在している可能性がある日和見菌について。
  • 短鎖脂肪酸産生、ビタミンB合成、胆汁酸代謝に関する機能的能力。
  • ディスバイオシス（腸内細菌叢の乱れ）、軽度の炎症、またはバリア機能低下を示唆するマーカー。
  • あなたの生態系を改善する可能性が高い、パーソナライズされた食事およびプレバイオティクス戦略。

Why gut health matters for healthspan

Healthspan is the number of years you spend in good functional health. The gut microbiome sits upstream of several systems that decide that: how you extract and store energy, how your immune system is trained, and how much low-grade inflammation you carry.[1]

Fibre-fermenting bacteria produce short-chain fatty acids such as butyrate, which feed the cells lining the colon and help maintain the barrier that keeps bacterial products out of the bloodstream. Reduced production of these compounds is a recurring finding in metabolic and inflammatory disease.[2]

Loss of microbial diversity has been described across obesity, type 2 diabetes, inflammatory bowel disease and cardiovascular disease, and in ageing cohorts a microbiome that drifts toward an unusual, individualised profile has been associated with better health and survival in older adults, while a conventional profile tracked with poorer outcomes.[3], [4]

Diet is the strongest and fastest lever available. Controlled feeding work shows the composition of the gut ecosystem shifting within days of a major dietary change, which is why a repeat test after a deliberate dietary period is informative.[5]

Much of this literature is associative, and a microbiome profile cannot tell you that you have or will develop a disease. The report is a map of your current ecosystem and a baseline you can move.

Reading your report

Diversity score

How many different organisms you carry and how evenly they are represented. Higher diversity is generally associated with a more resilient ecosystem in adults.

Beneficial organisms

Levels of the fibre-fermenting and butyrate-producing species associated with barrier integrity, with a note where any are notably low.

Opportunistic organisms

Species that are unremarkable in small numbers but unhelpful when over-represented, reported as relative abundance rather than a pass or fail.

Functional capacity

What your microbes are equipped to do: short-chain fatty acid production, B-vitamin synthesis and bile acid metabolism, which often matters more than the species list itself.

Dysbiosis and inflammation signatures

Patterns associated with impaired barrier function and low-grade inflammation, flagged for your doctor to read against your bloods.

Doctor's interpretation

Your ecosystem read alongside symptoms, diet history and blood results in the action-plan session, then translated into specific dietary changes.

What moves the result

Fibre diversity

The number of different plant foods eaten each week is one of the most consistent correlates of microbial diversity in population studies.

Fermented foods

Regular fermented food intake has been associated with increased microbiome diversity and lower inflammatory markers in a controlled dietary trial.

Targeted prebiotics

Specific fibres feed specific organisms. Your report indicates which are likely to be worth adding for your profile rather than a generic supplement.

Antibiotic stewardship

Courses of antibiotics reshape the ecosystem for weeks to months. Where a course is clinically needed, we plan the recovery period around it.

Alcohol and ultra-processed intake

Both are associated with reduced diversity and with signatures of impaired barrier function.

Sleep, stress and exercise

The gut-brain axis runs both ways. Sleep debt and sustained stress alter gut function, and regular exercise is associated with a more diverse profile.

対象となる方

  • 慢性的な消化器系の問題（膨満感、不規則な排便、食物不耐症など）がある方。
  • 自己免疫症状、繰り返す炎症、または皮膚疾患がある患者様。
  • 回復力、エネルギー、免疫力を最適化したいアスリートやハイパフォーマーの方。
  • 大幅な食事制限を行い、その効果を測定したい方。

再検査のタイミング： 食事療法中やディスバイオシスの治療中は3〜6ヶ月ごと、それ以外は毎年。

3つの柱にどのように適合するか

生物学的年齢を定義する単一の検査はありません。 マイクロバイオーム は、長寿データにおける他の2つの柱と並んで存在し、それぞれが他の検査では得られない洞察を提供します。これらを組み合わせることで、現代医学が提供できる最も完全な全体像が得られます。

柱

エピゲノム

DNAの塩基配列は生涯を通じてほとんど変化しませんが、DNA上に存在する化学修飾は、食事、睡眠、ストレス、運動、環境に応じて絶えず変化しています。.

詳細はこちら

Included in these tiers

Every tier includes a pre-test consultation, sample collection at our Orchard Road clinic, laboratory analysis, clinician-led interpretation, a written report and an action-plan session.

The Janus (The Baseline)

All-inclusive tier

The Apollo (The Functional)

All-inclusive tier

The Helios (The Performance)

All-inclusive tier

The Orion (The Complete)

All-inclusive tier

すべて見る 長寿スクリーニングパッケージリスト.

よくある質問

マイクロバイオーム - よくある質問

臨床チームが作成した明確な回答です。質問をタップすると直接リンクが表示されます。その他のご質問は、パーソナルコンシェルジュまでお問い合わせください。

  1. What does the microbiome test actually report?

    Your microbial diversity score, the balance of beneficial and opportunistic organisms, and a functional profile covering short-chain fatty acid production, vitamin synthesis and bile acid metabolism. Your concierge confirms the exact panel and laboratory before your kit ships.

  2. 事前にサプリメントや薬を中止する必要がありますか？

    過去4～6週間以内の抗生物質の使用はマイクロバイオームに大きな変化をもたらすため、可能であればその期間を避けてサンプリングをスケジュールします。プロバイオティクスやその他のサプリメントは通常継続可能です。キット発送前にコンシェルジュが詳細を確認します。

  3. 在宅キットは難しいですか？

    いいえ。キットには必要なものがすべて揃っており、説明書も同梱されています。採取は数分で完了し、サンプルは室温で数日間安定した状態を保てます。

  4. この検査で何を食べるべきか分かりますか？

    レポートには、お客様の特定の生態系がどのように反応するかに基づいた、パーソナライズされた食事に関する洞察が含まれています。具体的な計画への落とし込みは、医療チームとのアクションプラン相談で行われます。

  5. どのくらいの頻度で繰り返すべきですか？

    食事療法やディスバイオシスの治療を積極的に行っている場合は3〜6ヶ月ごと、それ以外の場合は安定性を追跡するために年1回をお勧めします。

  6. How does my gut microbiome relate to longevity and healthspan?

    Gut bacteria ferment fibre into short-chain fatty acids that maintain the gut barrier and influence inflammation, immune regulation and how you handle glucose and lipids. Loss of diversity is a recurring finding across metabolic and inflammatory disease, and in older adults a distinctive rather than conventional microbiome profile has been associated with better health and survival.

  7. Can a microbiome test diagnose IBS or IBD?

    No. It maps your ecosystem and flags patterns associated with dysbiosis and inflammation. Diagnosing irritable bowel syndrome, inflammatory bowel disease, coeliac disease or infection requires clinical assessment and its own tests, which your doctor will arrange if indicated.

  8. Should I take probiotics based on my result?

    Sometimes, but a targeted prebiotic fibre and a broader range of plant foods usually does more than a generic probiotic capsule. Your report indicates which organisms are under-represented, and your doctor advises accordingly.

  9. How fast can my microbiome change?

    Controlled feeding studies show the composition shifting within days of a major dietary change, though a durable shift takes sustained habit change. Retesting after three to six months of a deliberate dietary period is where the value sits.

  10. Does the sample tell you anything about my small intestine?

    Very little. A stool sample reflects the lower gut. Where symptoms point to the small intestine, your doctor will consider different investigations.

まだ質問がありますか？

パーソナルコンシェルジュが1営業日以内に機密を保持した上で回答いたします。

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What this test does not tell you

  • It is not a diagnostic test for coeliac disease, inflammatory bowel disease, infection or cancer. Those require their own investigations.
  • There is no single healthy microbiome. Results are read as a profile with strengths and gaps, not a score out of ten.
  • A stool sample reflects the lower gut. It says little about the small intestine, where some symptoms originate.
  • Day-to-day variation is real. Recent meals, travel and illness all move the picture, which is why sampling conditions are standardised.
  • Antibiotics in the previous four to six weeks meaningfully change results, so sampling is scheduled outside that window where possible.
  • Most published associations are correlational. A finding suggests a direction to work in rather than proving cause.

References

  1. [1] Lynch SV, Pedersen O. The human intestinal microbiome in health and disease. New England Journal of Medicine. 2016;375(24):2369-2379.
  2. [2] Koh A, De Vadder F, Kovatcheva-Datchary P, Backhed F. From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell. 2016;165(6):1332-1345.
  3. [3] Valdes AM, Walter J, Segal E, Spector TD. Role of the gut microbiota in nutrition and health. BMJ. 2018;361:k2179.
  4. [4] Wilmanski T, Diener C, Rappaport N, et al. Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nature Metabolism. 2021;3(2):274-286.
  5. [5] David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559-563.

追加の準備ができました マイクロバイオーム あなたの長寿ベースラインへ？

専属のヘルスコンシェルジュが、コンサルテーション、サンプリング、解釈、アクションプランのセッションまでを一貫して調整します。

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医学的監修： Dr. Julian Ng, MBBS (University of Sydney), MSc Microbiology (NUS), Cert. Men's Health (SMHS)

最終更新日 12 August 2026 · 次回更新予定 12 February 2027