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Longevity pillar · Singapore

Gut Microbiome Testing in Singapore

The microbial ecosystem in your gut shapes digestion, immunity, mood, inflammation and metabolism. We sequence the microorganisms present in your sample and report both who is there and what they are functionally doing.

  • SMC-registered doctors
  • MOH-licensed clinic (HCSA)
  • Mandarin Gallery, Orchard Road
  • Weekdays 10am-7pm · Sat-Sun 10am-5pm
  • Penyambut tetamu kesihatan peribadi

Apa yang diukur

Species identification

Bacteria and other microorganisms present in your gut, identified from the DNA in your sample.

Kepelbagaian mikrob

Skor kepelbagaian berserta keseimbangan relatif antara organisma berfaedah dan oportunistik.

Profil gen berfungsi

Apa yang mikrob anda sebenarnya boleh lakukan - penghasilan asid lemak rantai pendek, sintesis vitamin, kapasiti metabolik - bukan sekadar siapa yang ada di sana.

Penanda disbiosis dan keradangan

Tanda yang dikaitkan dengan risiko usus bocor, keradangan kronik, dan isyarat imun yang berubah.

Bagaimana ujian ini berfungsi

Sampel

Kit pengumpulan najis di rumah, stabil pada suhu bilik selama beberapa hari - tidak perlu disejukkan.

Tempoh Pusing Ganti

Your personal health concierge confirms the reporting timeline for your laboratory when your sample is collected.

Kaedah

DNA sequencing of the microorganisms in your stool sample, mapped against reference databases.

Mengapa kaedah ini

The report is read alongside your bloods and body composition by our medical team, then translated into a practical plan in an action-plan session. A test result on its own is not a plan.

Apa yang anda akan pelajari

  • Sama ada kepelbagaian mikrob anda berada dalam julat yang sihat.
  • Spesies berfaedah yang kekurangan dalam diri anda - dan organisma oportunistik yang mungkin berlebihan.
  • Kapasiti berfungsi untuk pengeluaran asid lemak rantaian pendek, sintesis vitamin B, metabolisme asid hempedu.
  • Penanda yang mencadangkan disbiosis, keradangan gred rendah, atau fungsi penghalang yang terjejas.
  • Strategi diet dan prebiotik diperibadikan yang berkemungkinan mengubah ekosistem anda.

Why gut health matters for healthspan

Healthspan is the number of years you spend in good functional health. The gut microbiome sits upstream of several systems that decide that: how you extract and store energy, how your immune system is trained, and how much low-grade inflammation you carry.[1]

Fibre-fermenting bacteria produce short-chain fatty acids such as butyrate, which feed the cells lining the colon and help maintain the barrier that keeps bacterial products out of the bloodstream. Reduced production of these compounds is a recurring finding in metabolic and inflammatory disease.[2]

Loss of microbial diversity has been described across obesity, type 2 diabetes, inflammatory bowel disease and cardiovascular disease, and in ageing cohorts a microbiome that drifts toward an unusual, individualised profile has been associated with better health and survival in older adults, while a conventional profile tracked with poorer outcomes.[3], [4]

Diet is the strongest and fastest lever available. Controlled feeding work shows the composition of the gut ecosystem shifting within days of a major dietary change, which is why a repeat test after a deliberate dietary period is informative.[5]

Much of this literature is associative, and a microbiome profile cannot tell you that you have or will develop a disease. The report is a map of your current ecosystem and a baseline you can move.

Reading your report

Diversity score

How many different organisms you carry and how evenly they are represented. Higher diversity is generally associated with a more resilient ecosystem in adults.

Beneficial organisms

Levels of the fibre-fermenting and butyrate-producing species associated with barrier integrity, with a note where any are notably low.

Opportunistic organisms

Species that are unremarkable in small numbers but unhelpful when over-represented, reported as relative abundance rather than a pass or fail.

Functional capacity

What your microbes are equipped to do: short-chain fatty acid production, B-vitamin synthesis and bile acid metabolism, which often matters more than the species list itself.

Dysbiosis and inflammation signatures

Patterns associated with impaired barrier function and low-grade inflammation, flagged for your doctor to read against your bloods.

Doctor's interpretation

Your ecosystem read alongside symptoms, diet history and blood results in the action-plan session, then translated into specific dietary changes.

What moves the result

Fibre diversity

The number of different plant foods eaten each week is one of the most consistent correlates of microbial diversity in population studies.

Fermented foods

Regular fermented food intake has been associated with increased microbiome diversity and lower inflammatory markers in a controlled dietary trial.

Targeted prebiotics

Specific fibres feed specific organisms. Your report indicates which are likely to be worth adding for your profile rather than a generic supplement.

Antibiotic stewardship

Courses of antibiotics reshape the ecosystem for weeks to months. Where a course is clinically needed, we plan the recovery period around it.

Alcohol and ultra-processed intake

Both are associated with reduced diversity and with signatures of impaired barrier function.

Sleep, stress and exercise

The gut-brain axis runs both ways. Sleep debt and sustained stress alter gut function, and regular exercise is associated with a more diverse profile.

Untuk siapa ia ditujukan

  • Sesiapa yang mempunyai masalah penghadaman kronik - kembung perut, tidak teratur, intoleransi makanan.
  • Pesakit dengan gejala autoimun, keradangan berulang atau masalah kulit.
  • Atlet dan individu berprestasi tinggi yang mengoptimumkan pemulihan, tenaga dan imuniti.
  • Sesiapa yang membuat perubahan diet yang ketara dan ingin mengukur kesannya.

Bila perlu diulang: Setiap 3-6 bulan semasa mengubah diet atau merawat disbiosis secara aktif; jika tidak, setiap tahun.

Bagaimana ia memenuhi tiga tonggak utama

Tiada ujian tunggal yang menentukan usia biologi. The mikrobiom terletak di samping dua lagi tonggak data jangka hayat - setiap satunya mendedahkan sesuatu yang tidak dapat dilihat oleh yang lain. Gabungkannya untuk gambaran paling lengkap yang boleh ditawarkan oleh perubatan semasa.

Included in these tiers

Every tier includes a pre-test consultation, sample collection at our Orchard Road clinic, laboratory analysis, clinician-led interpretation, a written report and an action-plan session.

Lihat penuh senarai pakej saringan jangka hayat.

Soalan Lazim

Mikrobiom - soalan lazim

Jawapan yang jelas, ditulis oleh pasukan klinikal kami. Ketik mana-mana soalan untuk pautan terusnya, atau hubungi Concierge Peribadi anda untuk perkara lain.

  1. What does the microbiome test actually report?

    Your microbial diversity score, the balance of beneficial and opportunistic organisms, and a functional profile covering short-chain fatty acid production, vitamin synthesis and bile acid metabolism. Your concierge confirms the exact panel and laboratory before your kit ships.

  2. Adakah saya perlu menghentikan sebarang suplemen atau ubat terlebih dahulu?

    Antibiotik dalam tempoh 4-6 minggu sebelumnya mengubah mikrobiom anda secara bermakna - jika boleh, kami menjadualkan pensampelan di luar tetingkap itu. Probiotik dan kebanyakan suplemen lain biasanya boleh diteruskan; concierge anda mengesahkan butiran sebelum kit anda dihantar.

  3. Adakah kit di rumah sukar digunakan?

    Tidak. Kit ini mengandungi semua yang anda perlukan berserta arahan bertulis. Pengumpulan sampel hanya mengambil masa beberapa minit dan sampel tersebut stabil pada suhu bilik selama beberapa hari.

  4. Adakah ujian ini akan memberitahu saya apa yang perlu dimakan?

    Laporan anda merangkumi pandangan diet yang diperibadikan berdasarkan tindak balas ekosistem khusus anda. Penterjemahan kepada pelan praktikal akan dilakukan semasa perundingan pelan tindakan bersama pasukan perubatan kami.

  5. Berapa kerap saya perlu mengulanginya?

    Setiap 3-6 bulan jika anda sedang aktif mengubah diet atau merawat disbiosis, jika tidak, lakukan setiap tahun untuk memantau kestabilan.

  6. How does my gut microbiome relate to longevity and healthspan?

    Gut bacteria ferment fibre into short-chain fatty acids that maintain the gut barrier and influence inflammation, immune regulation and how you handle glucose and lipids. Loss of diversity is a recurring finding across metabolic and inflammatory disease, and in older adults a distinctive rather than conventional microbiome profile has been associated with better health and survival.

  7. Can a microbiome test diagnose IBS or IBD?

    No. It maps your ecosystem and flags patterns associated with dysbiosis and inflammation. Diagnosing irritable bowel syndrome, inflammatory bowel disease, coeliac disease or infection requires clinical assessment and its own tests, which your doctor will arrange if indicated.

  8. Should I take probiotics based on my result?

    Sometimes, but a targeted prebiotic fibre and a broader range of plant foods usually does more than a generic probiotic capsule. Your report indicates which organisms are under-represented, and your doctor advises accordingly.

  9. How fast can my microbiome change?

    Controlled feeding studies show the composition shifting within days of a major dietary change, though a durable shift takes sustained habit change. Retesting after three to six months of a deliberate dietary period is where the value sits.

  10. Does the sample tell you anything about my small intestine?

    Very little. A stool sample reflects the lower gut. Where symptoms point to the small intestine, your doctor will consider different investigations.

Masih mempunyai soalan?

Concierge Peribadi anda akan membalas dalam masa satu hari bekerja - secara sulit.

What this test does not tell you

  • It is not a diagnostic test for coeliac disease, inflammatory bowel disease, infection or cancer. Those require their own investigations.
  • There is no single healthy microbiome. Results are read as a profile with strengths and gaps, not a score out of ten.
  • A stool sample reflects the lower gut. It says little about the small intestine, where some symptoms originate.
  • Day-to-day variation is real. Recent meals, travel and illness all move the picture, which is why sampling conditions are standardised.
  • Antibiotics in the previous four to six weeks meaningfully change results, so sampling is scheduled outside that window where possible.
  • Most published associations are correlational. A finding suggests a direction to work in rather than proving cause.

References

  1. [1] Lynch SV, Pedersen O. The human intestinal microbiome in health and disease. New England Journal of Medicine. 2016;375(24):2369-2379.
  2. [2] Koh A, De Vadder F, Kovatcheva-Datchary P, Backhed F. From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell. 2016;165(6):1332-1345.
  3. [3] Valdes AM, Walter J, Segal E, Spector TD. Role of the gut microbiota in nutrition and health. BMJ. 2018;361:k2179.
  4. [4] Wilmanski T, Diener C, Rappaport N, et al. Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nature Metabolism. 2021;3(2):274-286.
  5. [5] David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559-563.

Sedia untuk ditambah mikrobiom ke garis dasar umur panjang anda?

Penyambut tetamu kesihatan peribadi anda menyelaras sesi perundingan, persampelan, tafsiran dan pelan tindakan dari hujung ke hujung.

Disemak secara perubatan oleh Dr. Julian Ng, MBBS (University of Sydney), MSc Microbiology (NUS), Cert. Men's Health (SMHS)

Kali terakhir disemak 12 August 2026 · Semakan seterusnya 12 February 2027