Longevity pillar · Singapore
Gut Microbiome Testing in Singapore
The microbial ecosystem in your gut shapes digestion, immunity, mood, inflammation and metabolism. We sequence the microorganisms present in your sample and report both who is there and what they are functionally doing.
- SMC-registered doctors
- MOH-licensed clinic (HCSA)
- Mandarin Gallery, Orchard Road
- Weekdays 10am-7pm · Sat-Sun 10am-5pm
- Personal health concierge
Diversity score: 72 / 100 - Above average
Illustrative example, not a patient result. The diversity score is one component of a fuller profile.
What it measures
Species identification
Bacteria and other microorganisms present in your gut, identified from the DNA in your sample.
Microbial diversity
A diversity score plus the relative balance of beneficial vs opportunistic organisms.
Functional gene profile
What your microbes can actually do - short-chain fatty acid production, vitamin synthesis, metabolic capacity - not just who is there.
Dysbiosis and inflammation markers
Signatures associated with impaired barrier function, chronic inflammation, and altered immune signalling.
How the test works
Sample
At-home stool collection kit, shelf-stable for several days - no refrigeration required.
Turnaround
Your personal health concierge confirms the reporting timeline for your laboratory when your sample is collected.
Method
DNA sequencing of the microorganisms in your stool sample, mapped against reference databases.
Why this method
The report is read alongside your bloods and body composition by our medical team, then translated into a practical plan in an action-plan session. A test result on its own is not a plan.
What you'll learn
- Whether your microbial diversity is in a healthy range.
- Which beneficial species you are low in - and which opportunistic organisms may be over-represented.
- Functional capacity for short-chain fatty acid production, B-vitamin synthesis, bile acid metabolism.
- Markers suggesting dysbiosis, low-grade inflammation, or impaired barrier function.
- Personalised dietary and prebiotic strategies likely to move your ecosystem.
Why gut health matters for healthspan
Healthspan is the number of years you spend in good functional health. The gut microbiome sits upstream of several systems that decide that: how you extract and store energy, how your immune system is trained, and how much low-grade inflammation you carry.[1]
Fibre-fermenting bacteria produce short-chain fatty acids such as butyrate, which feed the cells lining the colon and help maintain the barrier that keeps bacterial products out of the bloodstream. Reduced production of these compounds is a recurring finding in metabolic and inflammatory disease.[2]
Loss of microbial diversity has been described across obesity, type 2 diabetes, inflammatory bowel disease and cardiovascular disease, and in ageing cohorts a microbiome that drifts toward an unusual, individualised profile has been associated with better health and survival in older adults, while a conventional profile tracked with poorer outcomes.[3], [4]
Diet is the strongest and fastest lever available. Controlled feeding work shows the composition of the gut ecosystem shifting within days of a major dietary change, which is why a repeat test after a deliberate dietary period is informative.[5]
Much of this literature is associative, and a microbiome profile cannot tell you that you have or will develop a disease. The report is a map of your current ecosystem and a baseline you can move.
Reading your report
Diversity score
How many different organisms you carry and how evenly they are represented. Higher diversity is generally associated with a more resilient ecosystem in adults.
Beneficial organisms
Levels of the fibre-fermenting and butyrate-producing species associated with barrier integrity, with a note where any are notably low.
Opportunistic organisms
Species that are unremarkable in small numbers but unhelpful when over-represented, reported as relative abundance rather than a pass or fail.
Functional capacity
What your microbes are equipped to do: short-chain fatty acid production, B-vitamin synthesis and bile acid metabolism, which often matters more than the species list itself.
Dysbiosis and inflammation signatures
Patterns associated with impaired barrier function and low-grade inflammation, flagged for your doctor to read against your bloods.
Doctor's interpretation
Your ecosystem read alongside symptoms, diet history and blood results in the action-plan session, then translated into specific dietary changes.
What moves the result
Fibre diversity
The number of different plant foods eaten each week is one of the most consistent correlates of microbial diversity in population studies.
Fermented foods
Regular fermented food intake has been associated with increased microbiome diversity and lower inflammatory markers in a controlled dietary trial.
Targeted prebiotics
Specific fibres feed specific organisms. Your report indicates which are likely to be worth adding for your profile rather than a generic supplement.
Antibiotic stewardship
Courses of antibiotics reshape the ecosystem for weeks to months. Where a course is clinically needed, we plan the recovery period around it.
Alcohol and ultra-processed intake
Both are associated with reduced diversity and with signatures of impaired barrier function.
Sleep, stress and exercise
The gut-brain axis runs both ways. Sleep debt and sustained stress alter gut function, and regular exercise is associated with a more diverse profile.
Who it's for
- Anyone with chronic digestive issues - bloating, irregularity, food intolerances.
- Patients with autoimmune symptoms, recurrent inflammation or skin conditions.
- Athletes and high performers optimising recovery, energy and immunity.
- Anyone making significant dietary changes who wants to measure the effect.
When to repeat: Every 3-6 months while actively changing diet or treating dysbiosis; otherwise annually.
How it fits the three pillars
No single test defines biological age. The microbiome sits alongside the other two pillars of longevity data - each reveals something the others cannot. Combine them for the most complete picture current medicine can offer.
Included in these tiers
Every tier includes a pre-test consultation, sample collection at our Orchard Road clinic, laboratory analysis, clinician-led interpretation, a written report and an action-plan session.
The Janus (The Baseline)
All-inclusive tier
The Apollo (The Functional)
All-inclusive tier
The Helios (The Performance)
All-inclusive tier
The Orion (The Complete)
All-inclusive tier
See the full longevity screening package list.
Microbiome - frequently asked questions
Clear answers, written by our clinical team. Tap any question for its direct permalink, or reach out to your Personal Concierge for anything else.
Your microbial diversity score, the balance of beneficial and opportunistic organisms, and a functional profile covering short-chain fatty acid production, vitamin synthesis and bile acid metabolism. Your concierge confirms the exact panel and laboratory before your kit ships.
Antibiotics within the previous 4-6 weeks meaningfully change your microbiome - if possible we schedule sampling outside that window. Probiotics and most other supplements can usually continue; your concierge confirms specifics before your kit ships.
Gut bacteria ferment fibre into short-chain fatty acids that maintain the gut barrier and influence inflammation, immune regulation and how you handle glucose and lipids. Loss of diversity is a recurring finding across metabolic and inflammatory disease, and in older adults a distinctive rather than conventional microbiome profile has been associated with better health and survival.
No. It maps your ecosystem and flags patterns associated with dysbiosis and inflammation. Diagnosing irritable bowel syndrome, inflammatory bowel disease, coeliac disease or infection requires clinical assessment and its own tests, which your doctor will arrange if indicated.
Still have a question?
Your Personal Concierge replies within one business day - confidentially.
What this test does not tell you
- It is not a diagnostic test for coeliac disease, inflammatory bowel disease, infection or cancer. Those require their own investigations.
- There is no single healthy microbiome. Results are read as a profile with strengths and gaps, not a score out of ten.
- A stool sample reflects the lower gut. It says little about the small intestine, where some symptoms originate.
- Day-to-day variation is real. Recent meals, travel and illness all move the picture, which is why sampling conditions are standardised.
- Antibiotics in the previous four to six weeks meaningfully change results, so sampling is scheduled outside that window where possible.
- Most published associations are correlational. A finding suggests a direction to work in rather than proving cause.
References
- [1] Lynch SV, Pedersen O. The human intestinal microbiome in health and disease. New England Journal of Medicine. 2016;375(24):2369-2379.
- [2] Koh A, De Vadder F, Kovatcheva-Datchary P, Backhed F. From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell. 2016;165(6):1332-1345.
- [3] Valdes AM, Walter J, Segal E, Spector TD. Role of the gut microbiota in nutrition and health. BMJ. 2018;361:k2179.
- [4] Wilmanski T, Diener C, Rappaport N, et al. Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nature Metabolism. 2021;3(2):274-286.
- [5] David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559-563.
Ready to add microbiome to your longevity baseline?
Your personal health concierge coordinates the consultation, sampling, interpretation and action-plan session end-to-end.
Medically reviewed by Dr. Julian Ng, MBBS (University of Sydney), MSc Microbiology (NUS), Cert. Men's Health (SMHS)
Last reviewed 12 August 2026 · Next review 12 February 2027