Comprehensive diagnostic panels for preventive and proactive health assessment, including longevity screening.
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Doctor-led treatments in hair restoration and clinical aesthetics.
Measured baselines for fitness, metabolism and biological ageing, reviewed with a doctor.
Longevity Screening · Orchard, Singapore
Measure how you are ageing across three layers: epigenetic biological age, your gut microbiome, and physical function including VO2 max and resting metabolic rate. Four cumulative tiers, clinician-led interpretation, and a personal health concierge from first sample to action plan.
Consultation is unhurried; the decision to proceed is always yours.
Chronological
45.0
Biological
42.3
Biological age: 42.3 vs chronological 45
Illustrative example, not a patient result.
Quick Answer
Longevity screening at Hisential Singapore measures three things that change over time and respond to treatment: your epigenetic biological age, your gut microbiome, and your physical function, including VO2 max and resting metabolic rate. The programme runs in four cumulative tiers, The Janus, The Apollo, The Helios and The Orion, each building on the one below. Every tier ends the same way, with an SMC-registered doctor translating the numbers into a plan you can follow.
Verified by Dr. Julian Ng, MBBS (University of Sydney), MSc Microbiology (NUS), Cert. Men's Health (SMHS) · Last reviewed 1 May 2026 · Next review 1 November 2026
Related: Executive Health Screening, VO2 Max Testing, RMR Testing, Optimisation Bundles.
No single test defines how you are ageing. We measure three layers because each one shows something the others cannot, and all three can be moved.
How you are ageing now. DNA methylation testing estimates your biological age, which is distinct from your chronological age and sensitive to sleep, training, nutrition and stress. Repeat it to see what is working.
Chronological
45.0
Biological
42.3
Biological age: 42.3 vs chronological 45
Illustrative example, not a patient result.
Your microbial ecosystem. Gut microbiome analysis reports diversity, the balance of beneficial and opportunistic organisms, and what your microbes are functionally doing for digestion, immunity and inflammation.
Diversity score: 72 / 100 - Above average
Illustrative example, not a patient result. The diversity score is one component of a fuller profile.
How your body performs today. VO2 max on a cycle ergometer and resting metabolic rate by indirect calorimetry give measured fitness, training zones and true daily energy needs instead of wearable estimates.
Most people focus on lifespan, meaning how long they will live. The more useful question is healthspan, meaning how many of those years are spent in good health. The gap between the two is the years lived in poor health, often concentrated in the final decade. Longevity screening exists to measure the things that influence that gap while they can still be changed.
Illustrative example, not a patient result.
The goal is not to flag every possible problem. It is to give you clarity. With real measurements in hand, you and your doctor can make more personalised decisions about training, nutrition, screening and treatment.
Each tier includes everything in the tier below it and adds a further layer of measurement. Every tier covers pre-test consultation, sample collection at our Orchard Road clinic, laboratory analysis, clinician-led interpretation, a written report and an action-plan session. Your personal health concierge confirms the full inclusions and fees for your chosen tier before anything is booked.
Tier 1
The Baseline
Where every longevity plan starts: your biological age, your gut ecosystem and a doctor-reviewed plan built around both.
Includes
Best for: Anyone who wants a first objective reading of how they are ageing, with a plan they can act on.
Tier 2
The Functional
Everything in The Janus, plus objective measures of how your body is built and how strong it is.
Everything in The Janus, plus
Best for: Patients who want muscle, fat distribution and functional strength measured alongside their biological age.
Tier 3
The Performance
Everything in The Apollo, plus laboratory measurement of how your body performs under load.
Everything in The Apollo, plus
Best for: Active patients, athletes and executives who want training set from measured cardiorespiratory fitness rather than estimates.
Tier 4
The Complete
Everything in The Helios, plus measurement of the energy your body burns at rest.
Everything in The Helios, plus
Best for: Patients who want every layer measured together and reviewed as one picture.
Panels are reviewed regularly and adjusted to your clinical needs. Your concierge confirms the exact inclusions for your tier before booking.
Optional add-on
The longevity tiers measure how you are ageing and how your body performs. A health screening adds the clinical bloodwork and imaging layer, which fine-tunes how your biological age is interpreted and looks for disease at an early, treatable stage. Either package can be added to any tier and reviewed in the same session.
82 biomarkers, hormonal and metabolic depth
The specialty tier. Male hormonal depth, insulin and HOMA-IR for metabolic health, advanced cardiac risk and specialty cancer markers, reviewed by our medical team.
Highlights
Pairs well with: Patients who want their biological age reading fine-tuned with hormonal, metabolic and cardiac bloodwork.
69 biomarkers, the broadest single-visit screening
The flagship health screening. Three ultrasound scans of your choice and a full cancer marker panel, coordinated by a Personal Health Concierge.
Highlights
Pairs well with: Patients who want the widest early detection layer alongside their longevity measurements.
Prefer a different level of screening? See all six health screening packages, or read about the multi-cancer early detection blood test, which can be added on its own.
An unhurried discussion of your health history, goals and what you most want to measure. Your concierge explains what each layer does and does not show. No pressure to schedule.
Best suited for
Anyone curious about what their biology is doing beyond standard blood work.
Bloods and saliva are collected at our Orchard Road clinic. The microbiome kit is completed at home. VO2 max and RMR testing is booked as a separate clinic session on the cycle ergometer.
Best suited for
Scheduled patients who have completed consultation.
Our medical team reviews everything before you see it and turns raw laboratory data into a written, plain-language report you can use.
Best suited for
Patients whose samples have been analysed and are awaiting their action-plan session.
One unhurried review session covers the findings, what matters most, and the nutrition, training, screening or treatment changes that follow. Your concierge stays with you for repeat testing.
Best suited for
Patients ready to convert measurements into a structured plan with medical oversight.
Self-check
A confidential, 30-second self-check. If two or more apply, a calm consultation is a reasonable next step. Your responses stay on this device only.
This self-check is informational only. A full clinical consultation is conducted before any test is recommended.
One dedicated contact who coordinates consultation, sample collection, laboratory tracking, results review and your follow-through plan, end to end.
Data is only useful when an SMC-registered doctor turns it into advice you can act on. Our medical team reviews every report before you see it.
VO2 max on a cycle ergometer and resting metabolic rate by indirect calorimetry, rather than figures inferred from a watch or a formula.
Every layer we measure can change. Tiers are designed around a baseline plus repeat readings so you can see whether your plan is working.
Your DNA letters barely change over your lifetime. The chemical tags sitting on top of your DNA, collectively called the epigenome, shift constantly in response to diet, sleep, stress, exercise, environment and illness. Reading those tags lets us estimate your biological age, which can be years younger or older than your chronological age.
What it measures: patterns of DNA methylation at thousands of sites, interpreted through peer-reviewed epigenetic clocks.
What you learn: your biological age against your chronological age, the gap between them, and, when repeated after 6 to 12 months, whether your changes are moving your biology.
Sample: saliva or blood collected at the clinic. Reporting: your concierge confirms the laboratory timeline at collection.
Your gut hosts roughly 100 trillion microorganisms whose diversity, composition and gene activity influence digestion, immunity, inflammation, mood, sleep, skin, hormones and weight regulation.
What you learn: your microbial diversity score, which organisms are over or under represented, a functional profile covering short-chain fatty acid production, vitamin synthesis and bile acid metabolism, and markers associated with dysbiosis and impaired barrier function.
Sample: an at-home stool collection kit, shelf stable for several days with no refrigeration required. Reporting: confirmed by your concierge before the kit ships.
Cardiorespiratory fitness is one of the most closely studied measures of long-term health. We measure it directly rather than estimating it from a wearable.
VO2 max is measured on a cycle ergometer with a graded protocol while your expired gases are analysed breath by breath, giving your peak oxygen uptake, ventilatory thresholds and heart-rate training zones.
Resting metabolic rate is measured after a short rest using indirect calorimetry, giving your actual daily energy requirement and substrate use instead of a population formula.
Read our full VO2 max testing and RMR testing pages for preparation details.
Every tier begins with a doctor consultation. We review your history, current symptoms, training, family history and what you want out of the programme, then confirm which tier fits.
Your personal health concierge is introduced at this point and stays with you through collection, reporting and follow-through.
There is no obligation to proceed on the day. Many patients take the recommendation away and book later.
Bloods and saliva are collected at our Orchard Road clinic, usually in a single visit.
The microbiome kit is completed at home and returned by courier or dropped back to the clinic.
VO2 max and RMR are booked as a separate clinic session. RMR is measured fasted, VO2 max follows on the cycle ergometer.
Each sample is processed at an accredited specialist laboratory. Turnaround differs by test, and your personal health concierge confirms the timeline for your samples at collection and keeps you updated.
Physical function results are available immediately after the session and are interpreted with the rest of your data.
We do not release raw laboratory data without a clinician review session. Results without context are not useful and can cause unnecessary worry.
Once your results are in, our medical team prepares a written report and books an unhurried review session, typically 60 minutes and longer for the higher tiers.
In the session you cover: the headline findings in plain language, what is actionable now and what is best monitored, the specific nutrition, training, screening or treatment adjustments that follow, any referral that is warranted, and when to repeat each measure.
After the session, your concierge stays available on WhatsApp and coordinates the next steps you decide to take.
Q:
How long does it take to get my results back?
It depends on the laboratory handling each sample. Your concierge confirms the timeline at collection and tracks every sample until your review is booked. VO2 max and RMR results are available on the day.
Q:
Is any of this covered by insurance in Singapore?
Coverage for preventive and predictive testing is limited. We provide an itemised invoice for personal claims, though most patients pay out of pocket.
Q:
Can I share my results with my regular doctor?
Yes. Your written report is yours, and we can coordinate directly with another clinician on your behalf.
Q:
Can I start at one tier and move up later?
Yes. The tiers are cumulative, so patients often begin with The Janus and add the functional or performance layers at their next review.
Q:
Do you offer whole genome sequencing?
No. The Singapore programme focuses on measures that change over time and respond to treatment: epigenetics, the gut microbiome and physical function.
Clear answers, written by our clinical team. Tap any question for its direct permalink, or reach out to your Personal Concierge for anything else.
Most biological change happens quietly for years before symptoms appear. Longevity screening measures what is happening now, so modifiable findings such as an accelerated biological age, a dysbiotic gut or poor cardiorespiratory fitness can be addressed while there is still room to act.
Three layers. Epigenetics gives your biological age from DNA methylation. Gut microbiome analysis reads the microbial ecosystem shaping digestion, immunity and inflammation. Physical function testing, including VO2 max and resting metabolic rate on a cycle ergometer, measures how your body performs today.
The epigenetic clocks we use are peer reviewed and validated. A single reading is a snapshot, so the number is most useful as something you track. We recommend a baseline plus a repeat reading 6 to 12 months later to separate real change from measurement variation.
Epigenetic age every 6 to 12 months while you are actively making changes. Gut microbiome every 3 to 6 months while changing diet or treating dysbiosis, otherwise annually. VO2 max and resting metabolic rate every 3 to 6 months during a structured training block.
Fees are private and payable in full at the visit. MediSave, CHAS and Healthier SG subsidies do not apply. Some insurance plans cover consultations and investigations on a reimbursement basis: you pay the clinic and claim back from your insurer afterwards. The concierge provides the documentation you need and helps with the claim paperwork. Instalment payment is available: ask the concierge about the options before your visit.
Still have a question?
Your Personal Concierge replies within one business day - confidentially.
Ready to start?
Speak with our medical team and your personal health concierge at Mandarin Gallery, Orchard Road.
Hisential Orchard Clinic
333A Orchard Road, #04-13 Mandarin Gallery,
Singapore 238897
Phone: +65 3125 6028
WhatsApp: +65 8963 5233
Hours: Weekdays 10am-7pm · Sat-Sun 10am-5pm
Parking: Mandarin Gallery car park. Public transit: Somerset MRT (2-min walk) or Orchard MRT (5-min walk).
Measured cardiorespiratory fitness on a cycle ergometer with breath-by-breath gas analysis, plus training zones.
Measured resting calorie burn by indirect calorimetry, with a doctor-reviewed daily energy target.
Structured follow-through for performance, weight management, and sleep and stress, built on your screening results.
Comprehensive medical and laboratory work-up, often the entry point to longevity screening.
Biomarker panel that pairs naturally with microbiome and epigenetic data for a nutrition plan.
Medically reviewed by Dr. Julian Ng, MBBS (University of Sydney), MSc Microbiology (NUS), Cert. Men's Health (SMHS)
Last reviewed 1 May 2026 · Next review 1 November 2026
